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PTX3 Polymorphisms and Invasive Mold Infections After Solid Organ Transplant

Authors :
Wójtowicz, A.
Lecompte, T.D.
Bibert, S.
Manuel, O.
Rüeger, S.
Berger, C.
Boggian, K.
Cusini, A.
Garzoni, C.
Hirsch, H.
Khanna, N.
Mueller, N.J.
Meylan, P.R.
Pascual, M.
van Delden, C.
Bochud, P.Y.
University of Zurich
Bochud, Pierre-Yves
Swiss Transplant Cohort Study
Achermann, R.
Aubert, JD.
Baumann, P.
Beldi, G.
Benden, C.
Berger, C.
Binet, I.
Bochud, PY.
Boely, E.
Bucher, H.
Bühler, L.
Carell, T.
Catana, E.
Chalandon, Y.
de Geest, S.
de Rougemont, O.
Dickenmann, M.
Duchosal, M.
Fehr, T.
Ferrari-Lacraz, S.
Garzoni, C.
Gasche, Y.
Soccal, PG.
Giostra, E.
Golshayan, D.
Good, D.
Hadaya, K.
Hess, C.
Hillinger, S.
Hirsch, HH.
Hofbauer, G.
Huynh-Do, U.
Immer, F.
Klaghofer, R.
Koller, M.
Kuntzen, T.
Laesser, B.
Lehmann, R.
Lovis, C.
Manuel, O.
Marti, HP.
Martin, PY.
Meylan, P.
Mohacsi, P.
Morard, I.
Morel, P.
Mueller, U.
Mueller, NJ.
Mueller-McKenna, H.
Müller, T.
Müllhaupt, B.
Nadal, D.
Nair, G.
Pascual, M.
Passweg, J.
Ziegler, CP.
Rick, J.
Roosnek, E.
Rosselet, A.
Rothlin, S.
Ruschitzka, F.
Schanz, U.
Schaub, S.
Seiler, C.
Semmo, N.
Stampf, S.
Steiger, J.
Toso, C.
Tsinalis, D.
Van Delden, C.
Venetz, JP.
Villard, J.
Wick, M.
Wilhelm, M.
Yerly, P.
Source :
CLINICAL INFECTIOUS DISEASES, Clinical Infectious Diseases, Vol. 61, No 4 (2015) pp. 619-622, Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, vol. 61, no. 4, pp. 619-622
Publication Year :
2015

Abstract

Donor PTX3 polymorphisms were shown to influence the risk of invasive aspergillosis among hematopoietic stem cell transplant recipients. Here, we show that PTX3 polymorphisms are independent risk factors for invasive mold infections among 1101 solid organ transplant recipients, thereby strengthening their role in mold infection pathogenesis and patients' risk stratification.

Subjects

Subjects :
10234 Clinic for Infectious Diseases
ddc:616
10219 Clinic for Gastroenterology and Hepatology
10036 Medical Clinic
10209 Clinic for Cardiology
C-Reactive Protein/genetics
Female
Fungi/isolation & purification
Humans
Immunocompromised Host
Male
Mycoses/genetics
Mycoses/immunology
Organ Transplantation/adverse effects
Polymorphism, Genetic
Prospective Studies
Serum Amyloid P-Component/genetics
610 Medicine & health
2725 Infectious Diseases
2726 Microbiology (medical)

Details

ISSN :
10584838
Volume :
61
Issue :
4
Database :
OpenAIRE
Journal :
CLINICAL INFECTIOUS DISEASES
Accession number :
edsair.dedup.wf.001..6552fe805ab061351b7fcdd75858410c
Full Text :
https://doi.org/10.1093/cid/civ386
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