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Prevalence and associated behavioral symptoms of depression in mild cognitive impairment and dementia due to Alzheimer's disease
Prevalence and associated behavioral symptoms of depression in mild cognitive impairment and dementia due to Alzheimer's disease
- Source :
- International Journal of Geriatric Psychiatry 28 (2013) 9, International Journal of Geriatric Psychiatry, 28(9), 947-958. Wiley, International journal of geriatric psychiatry: a journal of the psychiatry of late life and allied sciences, International Journal of Geriatric Psychiatry, 28(9), 947-958
- Publication Year :
- 2013
-
Abstract
- Background: Mild cognitive impairment (MCI) is a clinical concept that categorizes subjects who are in an intermediate cognitive state between normal aging and dementia. The aims of this study are to determine the prevalence of significant depressive symptoms in MCI and Alzheimer's disease (AD) patients and to characterize the behavior associated with significant depressive symptoms in MCI and AD patients. Methods: A cross-sectional analysis of baseline data from a prospective, longitudinal study on behavioral symptoms of dementia and MCI was performed. The study population consisted of 270 MCI and 402 AD patients. Behavioral assessment was performed by means of Middelheim Frontality Score, Behavioral Pathology in Alzheimer's Disease Rating Scale (Behave-AD) and Cohen-Mansfield Agitation Inventory. The presence of significant depressive symptoms was defined as a Cornell Scale for Depression in Dementia total score >7. Results: The prevalence of significant depressive symptoms in AD patients (25%) was higher compared with MCI patients (16%) (p = 0.005). Patients with significant depressive symptoms showed an increased severity of frontal lobe symptoms, behavioral symptoms and agitation (Middelheim Frontality Score, Behave-AD and Cohen-Mansfield Agitation Inventory total scores; p
- Subjects :
- Male
AGOMELATINE
DISORDERS
behavioral symptoms
Neuropsychological Tests
DIAGNOSIS
behavioral disciplines and activities
Cornell Scale
depressive symptoms
mild cognitive impairment
Alzheimer Disease/psychology
Behavioral Symptoms/epidemiology
Cognitive Dysfunction/psychology
Prevalence
Humans
Prospective Studies
VALIDITY
POPULATION
Aged
NEUROPSYCHIATRIC SYMPTOMS
Psychiatric Status Rating Scales
Medicine(all)
WORKING GROUP
Depressive Disorder/epidemiology
Middle Aged
FRONTOTEMPORAL DEMENTIA
Alzheimer's disease
Cross-Sectional Studies
frontal lobe symptoms
depression
Female
Human medicine
AGITATION
aged, 80 and over
dementia
Subjects
Details
- Language :
- English
- ISSN :
- 08856230
- Database :
- OpenAIRE
- Journal :
- International Journal of Geriatric Psychiatry 28 (2013) 9, International Journal of Geriatric Psychiatry, 28(9), 947-958. Wiley, International journal of geriatric psychiatry: a journal of the psychiatry of late life and allied sciences, International Journal of Geriatric Psychiatry, 28(9), 947-958
- Accession number :
- edsair.dedup.wf.001..88e63a4a60a3fe129df7f46a515cc27e