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Changes in Lean Mass, Absolute and Relative Muscle Strength, and Physical Performance After Gastric Bypass Surgery
- Source :
- The Journal of clinical endocrinology and metabolism, vol 104, iss 3
- Publication Year :
- 2019
- Publisher :
- eScholarship, University of California, 2019.
-
Abstract
- ContextBariatric surgery results in reduced muscle mass as weight is lost, but postoperative changes in muscle strength and performance are incompletely understood.ObjectiveTo examine changes in body composition, strength, physical activity, and physical performance following Roux-en-Y gastric bypass (RYGB).Design, participants, outcomesIn a prospective cohort of 47 adults (37 women, 10 men) aged 45 ± 12 years (mean ± SD) with body mass index (BMI) 44 ± 8 kg/m2, we measured body composition by dual-energy X-ray absorptiometry, handgrip strength, physical activity, and physical performance (chair stand time, gait speed, 400-m walk time) before and 6 and 12 months after RYGB. Relative strength was calculated as absolute handgrip strength/BMI and as absolute strength/appendicular lean mass (ALM).ResultsParticipants experienced substantial 12-month decreases in weight (-37 ± 10 kg or 30% ± 7%), fat mass (-48% ± 12%), and total lean mass (-13% ± 6%). Mean absolute strength declined by 9% ± 17% (P < 0.01). In contrast, relative strength increased by 32% ± 25% (strength/BMI) and 9% ± 20% (strength/ALM) (P < 0.01 for both). There were clinically significant postoperative improvements in all physical performance measures, including mean improvement in gait speed of >0.1 m/s (P < 0.01) and decrease in 400-m walk time of nearly a full minute.ConclusionsIn the setting of dramatic weight loss, lean mass and absolute grip strength declined after RYGB. However, relative muscle strength and physical function improved meaningfully and are thus noteworthy positive outcomes of gastric bypass.
- Subjects :
- Adult
Male
Clinical Sciences
Gastric Bypass
Paediatrics and Reproductive Medicine
Endocrinology & Metabolism
Clinical Research
Weight Loss
Humans
Obesity
Prospective Studies
Morbid
Absorptiometry
Aged
Nutrition
6.7 Physical
Hand Strength
Prevention
Evaluation of treatments and therapeutic interventions
Skeletal
Middle Aged
Physical Functional Performance
Photon
Treatment Outcome
Body Composition
Muscle
Female
Digestive Diseases
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- The Journal of clinical endocrinology and metabolism, vol 104, iss 3
- Accession number :
- edsair.dedup.wf.001..b9463aad09014ba4b2c365f31c3be204