Clinical value of thrombelastography in diagnosis of heat stroke combined with disseminated intravascular coagulation and judgement of prognosis

Objective To investigate the clinical value of thrombelastography (TEG) in the diagnosis and prognosis judgement of heatstroke with disseminated intravascular coagulation (DIC). Methods Thirty-two patients with heatstroke were selected from the 94th Hospital of Chinese PLA during Jun. 2016 and Sep. 2017. The general information and laboratory test of the patients within two hours after admission were collected or performed, including prothrombin time, activated partial thromboplastin time (APTT), fibrinogen (FIB), thrombin time (TT), plasma fibrin degradation products (FDP), D-Dimer (D-D), antithrombin Ⅲ (ATⅢ) and the TEG parameters. The TEG-DIC and ISTH-DIC criteria were compared. The patients were divided into survival group (n=24) and death group (n=8) according to prognosis. The results of coagulation test and thromboelastograph were compared. The relationship between TEG score and mortality were investigated. Results Compared with the reaction time [R value, 6.5(5.7-11.6)min] and kinetics of clot development [K value, 3.8(2.3- 6.3)min] of survival group, the R value [30.9(10.28-88.58)min] and K value [22.4(4.90-41.63)min] of death group were significantly higher (P