Back to Search
Start Over
Correlation of routine ultrasound features and BRAFV600E gene to the cervical lymph node metastasis of thyroid papillary carcinoma
- Source :
- Medical Journal of Chinese People's Liberation Army, Vol 44, Iss 9, Pp 757-762 (2019)
- Publication Year :
- 2019
- Publisher :
- Editorial Board of Medical Journal of Chinese People's Liberation Army, 2019.
-
Abstract
- Objective To investigate the correlation of routine ultrasound features and BRAFV600E gene to the cervical lymph node metastasis (CLNM) of thyroid papillary carcinoma (PTC). Methods A hundred and seven patients with thyroid papillary carcinoma who underwent thyroid gland resection and cervical lymph node dissection in the First Medical Center of Chinese PLA General Hospital from January to December 2018 were recruited as study subjects, including 56 patients in the metastatic group and 51 patients in the non-metastatic group. Ultrasound examination and BRAFV600E gene detection were performed, and the indicators obtained were compared between the two groups including gender, age, focus position (upper middle or inferior), close to the capsule or to the isthmus, focus located in the left or right lobes, single or multiple, maximum diameter, aspect ratio, boundary, shape, internal echo, internal components, peripheral halos, calcification, microcalcification, color Doppler features, Hashimoto's disease, and BRAFV600E gene mutation. Logistic regression analysis was conducted for gender, age, close to the capsule or to the isthmus, maximum diameter, shape, calcification, microcalcification, color Doppler features, Hashimoto's disease, and BRAFV600E gene mutation to establish a predictive model of cervical lymph node metastasis in patients with thyroid papillary carcinoma, and the predictive efficacy of the model was evaluated. Results The results compared between the two groups showed that statistically significant differences existed in gender, age, maximum diameter of the lesion, close to capsule, close to isthmus, shape, acoustic halo, calcification and microcalcification (P
- Subjects :
- lcsh:R5-920
lcsh:R
lcsh:Medicine
lcsh:Medicine (General)
Subjects
Details
- Language :
- Chinese
- ISSN :
- 05777402
- Volume :
- 44
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Medical Journal of Chinese People's Liberation Army
- Accession number :
- edsair.doajarticles..2997c162d86b8a9e7181033b3ef56a17