ChemInform Abstract: A Simple and Convenient High Yielding Synthesis of Substituted Isoindolines

Authors :: Gamal A. El-Hiti
Keith Smith
Ahmed Fekri
Amany S. Hegazy
Source :: ChemInform. 41
Publication Year :: 2010
Publisher :: Wiley, 2010.
Abstract: Trifluoroacetic anhydride-induced dehydration of substituted 2-(pivaloylaminomethyl)phenyl- and 2-(dimethylaminocarbonylmethyl)phenylmethanols gives the corresponding isoindolines in excellent yields when there are aryl substituents at the methanol carbon atom.

Subjects :: chemistry.chemical_compound
Carbon atom
Chemistry
Simple (abstract algebra)
Aryl
medicine
Phenylmethanol
General Medicine
Methanol
Dehydration
medicine.disease
Combinatorial chemistry
High yielding

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