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Safety and preliminary efficacy of talimogene laherparepvec (T-VEC) in combination (combo) with pembrobrolizumab (Pembro) in patients (pts) with recurrent or metastatic squamous cell carcinoma of the head and neck (R/M HNSCC): A multicenter, phase 1b study (MASTERKEY-232)
- Source :
- Journal of Clinical Oncology. 36:6036-6036
- Publication Year :
- 2018
- Publisher :
- American Society of Clinical Oncology (ASCO), 2018.
-
Abstract
- 6036Background: We evaluated the safety and efficacy of the combo of T-VEC, the first FDA-approved oncolytic immunotherapy that enhances systemic antitumor immune responses, and Pembro, an immune c...
- Subjects :
- 0301 basic medicine
Oncology
Cancer Research
medicine.medical_specialty
animal diseases
medicine.medical_treatment
chemical and pharmacologic phenomena
03 medical and health sciences
0302 clinical medicine
Immune system
Internal medicine
medicine
Basal cell
In patient
Head and neck
business.industry
Immunotherapy
biochemical phenomena, metabolism, and nutrition
equipment and supplies
Oncolytic virus
030104 developmental biology
030220 oncology & carcinogenesis
bacteria
Talimogene laherparepvec
business
Subjects
Details
- ISSN :
- 15277755 and 0732183X
- Volume :
- 36
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Oncology
- Accession number :
- edsair.doi...........005d1298798973f6e0b4118835556c3b