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Oxalic acid dihydrate and proline based low transition temperature mixture: An efficient synthesis of spiro [diindenopyridine-indoline] triones derivatives
- Source :
- Journal of Molecular Liquids. 219:573-578
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- The new facile approach has been developed for the synthesis of spiro [diindenopyridine-indoline] triones under the umbrella of green chemistry. The developed protocol is endowed with the use of low transition temperature mixture as a green reaction medium, operational simplicity, easy workup procedures, good to excellent product yields, and non-chromatographic purification procedure. Since indenone fused motifs have a broad spectrum of biological activities, this protocol is expected to find application in the combinatorial synthesis of biologically active compounds.
- Subjects :
- Green chemistry
010405 organic chemistry
Chemistry
Indenone
Isatin
Transition temperature
010402 general chemistry
Condensed Matter Physics
Combinatorial synthesis
01 natural sciences
Atomic and Molecular Physics, and Optics
0104 chemical sciences
Electronic, Optical and Magnetic Materials
chemistry.chemical_compound
Indoline
Materials Chemistry
Organic chemistry
Proline
Physical and Theoretical Chemistry
OXALIC ACID DIHYDRATE
Spectroscopy
Subjects
Details
- ISSN :
- 01677322
- Volume :
- 219
- Database :
- OpenAIRE
- Journal :
- Journal of Molecular Liquids
- Accession number :
- edsair.doi...........013a820c2ac5ae184d749923991855bc