Extracellular vesicle-derived microRNA biomarkers: goals and pitfalls

Authors :: Christian Grätz
Benedikt Kirchner
Stefanie Hermann
Michael W. Pfaffl
Source :: Extracellular vesicles as biomarkers – in pathophysiology, physical education and home office?. 2:42-47
Publication Year :: 2020
Publisher :: Trillium GmbH Medizinischer Fachverlag, 2020.
Abstract: Liquid biopsy-derived extracellular vesicles (EVs) are an auspicious source for transcriptomic biomarker studies. Here, we review the potential of EV microRNAs (miRNAs) biomarkers, exemplary outline commonly used methods to elucidate new biomarker signatures, and pivotally discuss their applicability at present. Keywords: extracellular vesicles, liquid biopsies, transcriptomic biomarkers, microRNAs

Subjects :: 0301 basic medicine
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
030220 oncology & carcinogenesis
microRNA
Extracellular vesicle
Biology
Cell biology

ISSN :: 26988739
Volume :: 2
Database :: OpenAIRE
Journal :: Extracellular vesicles as biomarkers – in pathophysiology, physical education and home office?
Accession number :: edsair.doi...........0285d9f83d3fac6dc8f7430cd433c58b
Full Text :: https://doi.org/10.47184/tev.2020.01.04