ChemInform Abstract: Geminal Alkene-Alkyne Cross Metathesis Using a Relay Strategy

A relay strategy was employed to achieve an intermolecular ene–yne metathesis between 1,1-disubstituted alkenes and alkynes. The relay serves to activate an unreactive alkene which will not participate in ene-yne metathesis. The new relay cross ene–yne metathesis gives rise to 1,1,3-trisubstituted-1,3-dienes previously inaccessible by direct ene–yne metathesis methods.