ChemInform Abstract: Direct Double Electrophilic Fluorination of Allenoic Acids and Tosylamides to Give 1,1-Difluoroallylic Heterocyclic Compounds

A novel and facile preparation of 1,1-difluoroallyl substituted five-membered lactones or pyrrolidines in moderate yields through direct double electrophilic fluorination of 4,5-allenoic acids or tosylamides with SelectfluorTM F-TEAD-BF4 is described.