Hemodynamic effects of nifedipine tocolysis

Aim To describe the effects of nifedipine tocolysis on blood pressure and heart rate in non-hypertensive women. Methods This was a retrospective study from 2001 to 2011 to compare blood pressures and heart rates among non-hypertensive women on nifedipine tocolysis up to 8 h after nifedipine initiation. Measurements at 20–60 and 61–120 min were compared to assess the differential effects of dosing on hemodynamics and reflected the effects of the initial and complete loading doses, respectively. Charts were reviewed for hypotension-related emergent delivery. Results One hundred and thirty-eight patients were included. Over the 8-h study interval, mean systolic blood pressure (P