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Development and Demonstration of a Co-feed Process to Address Form and Physical Attribute Control of the Gefapixant (MK-7264) Citrate Active Pharmaceutical Ingredient
- Source :
- Organic Process Research & Development. 25:541-551
- Publication Year :
- 2021
- Publisher :
- American Chemical Society (ACS), 2021.
-
Abstract
- The final chemical transformation and isolation in the synthesis of an active pharmaceutical ingredient (API), referred to as the Pure Step, is often chemically simple but scientifically, operation...
Details
- ISSN :
- 1520586X and 10836160
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- Organic Process Research & Development
- Accession number :
- edsair.doi...........050d565e3d00180c82c678ebb7b2a798
- Full Text :
- https://doi.org/10.1021/acs.oprd.0c00488