Reduction of .beta.-hydroxy ketones with catecholborane. A stereoselective approach to the synthesis of syn-1,3-diols

Authors :: David Evans
Amir H. Hoveyda
Source :: The Journal of Organic Chemistry. 55:5190-5192
Publication Year :: 1990
Publisher :: American Chemical Society (ACS), 1990.
Abstract: The stereoselective reduction of acyclic β-hydroxy ketones to syn 1,3-diols may be achieved with the mild reducing agent catecholborane. In certain instances reaction stereoselectivity may be enhanced through rhodium (I) catalysis

Subjects :: Reduction (complexity)
chemistry.chemical_compound
Chemistry
Reducing agent
Organic Chemistry
chemistry.chemical_element
Stereoselectivity
Beta (finance)
Medicinal chemistry
Catecholborane
Catalysis
Rhodium

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