A RARE CASE OF OVARIAN HYPERSTIMULATION AFTER CLOMIPHENE CITRATE RESULTING IN TORSION AND RUPTURE

Ovarian hyperstimulation is a dreaded complication of ovarian stimulation protocols in infertility and is known to complicate about 5-10% of ART cycles. Following gonadotropin therapy, OHSS (Ovarian hyperstimulation) usually develops several days after assisted ovulation or oocyte retrieval. But it is quite rare with clomiphene therapy which in general causes unifollicular development. Here we are presenting an interesting case of ovarian hyperstimulation which presented with rupture and massive hemoperitoneum resulting in hemodynamic instability. It is all the more rare because the agent used for ovarian stimulation was clomiphene citrate at its minimum dose.