Phosphonate Isosteres of Acyclovir and Ganciclovir Honophosphates Synthesis and Anti-Herpesvirus Activity

Authors :: Peter F. Misco
Bing Yu Luh
John C. Martin
Choung U. Kim
Source :: Nucleosides and Nucleotides. 10:483-485
Publication Year :: 1991
Publisher :: Informa UK Limited, 1991.
Abstract: Isosteric phosphonate analogues of acyclovir and ganciclovir monophosphates were synthesized. The new phosponates exhibited good anti-herpes activity.

Subjects :: Ganciclovir
viruses
virus diseases
biochemical phenomena, metabolism, and nutrition
Biochemistry
Phosphonate
Combinatorial chemistry
chemistry.chemical_compound
stomatognathic system
chemistry
Genetics
medicine
heterocyclic compounds
medicine.drug

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