ChemInform Abstract: Versatile Palladium(II)-Catalyzed Suzuki-Miyaura Coupling in Ethanol with a Novel, Stabilizing Ligand

Suzuki–Miyaura coupling reactions of arylboronic acids with aryl bromides were mediated by PdCl2 and bdppmapy (N,N-bis-(diphenylphosphanylmethyl)-2-aminopyridine) that both stabilizes and solubilizes the catalyst in predominantly ethanol as a solvent. Excellent yields for a wide variety of substrates were obtained under relatively mild conditions in this ‘green’ solvent.