Recent Advances in Liposome

Liposomes as artificial colloidal vesicular structure having hydrophilic core in a lipid bilayer membrane became one of the most tremendously explored drug delivery system. These spherical vesicles consist of amphiphilic molecule like cholesterol, sterols and can be used to deliver both hydrophilic drugs as well as lipophilic drug. These vesicles are differentiated on the basis of size, composition, method of preparation and application. Liposomes are biodegradable, nonimmunogenic, biocompatible, provide targeted and prolonged release, change pharmacokinetic and pharmacodynamic attribute of drug, they find wide clinical application as diagnostic, antimicrobial, anticancer, vaccine adjuvant and cosmetics. Expanding application show promising sign for future development in liposome. The present review provides information about liposome in drug deliver, their composition, structure, different method of preparation, various types of liposome, clinical applications of liposome, strategies, marketed formulation.