GW29-e1460 S-Nitrosylation of NF-kappaB p65 Inhibits H2O2-Induced endothelial senescence

Nuclear factor-κB plays a critical role in endothelial senescence. However, the mechanisms remain unclear. We hypothesized that the alteration of S-Nitrosylation of NF-κB p65 may contribute to hydrogen peroxide-induced endothelial cell senescence. The human umbilical vein endothelial cells (