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Profound reduction of invariant natural killer T cells in the peripheral blood of a patient with interleukin-1 receptor-associated kinase 4 deficiency
- Source :
- Immunology Letters. 132:86-89
- Publication Year :
- 2010
- Publisher :
- Elsevier BV, 2010.
-
Abstract
- We previously described a patient with a history of frequent life-threatening pneumonias, infections with bacterial pathogens, interleukin 1 receptor-associated kinase 4 deficiency, and failure to maintain antibody titers to polysaccharide antigens or to a neoantigen bacteriophage. In the present study, we show that the patient's peripheral blood mononuclear cells have a profound deficiency of invariant natural killer T cells.
Details
- ISSN :
- 01652478
- Volume :
- 132
- Database :
- OpenAIRE
- Journal :
- Immunology Letters
- Accession number :
- edsair.doi...........091ddf9c3e20a4f746ac4ca5ccdcccad
- Full Text :
- https://doi.org/10.1016/j.imlet.2010.04.011