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State of the art paper Tuberculosis and diabetes mellitus – an underappreciated association
- Source :
- Archives of Medical Science. 5:1019-1027
- Publication Year :
- 2014
- Publisher :
- Termedia Sp. z.o.o., 2014.
-
Abstract
- The current review presents up-to-date knowledge on tuberculosis (TB) in diabetic patients. On the basis of available literature, there is little doubt about the close relationship between these two conditions. Diabetes mellitus in this association may still contribute substantially to the burden of TB and negatively affect control of the latter. Chronic hyperglycemia at least to some extent may alter the clinical manifestation, radiological appearance, treatment outcome and prognosis of TB. Although the pathogenesis is not clear, diabetes may impair both innate and adaptive immune responses to Mycobacterium tuberculosis. Eventually, effective screening and dual management of the diseases have to be addressed both in low- and high-income countries in order to limit the negative effects of the forthcoming global diabetes epidemic.
- Subjects :
- medicine.medical_specialty
Tuberculosis
biology
business.industry
Treatment outcome
General Medicine
Clinical manifestation
biology.organism_classification
Bioinformatics
medicine.disease
Mycobacterium tuberculosis
Pathogenesis
Immune system
Chronic hyperglycemia
Diabetes mellitus
medicine
Intensive care medicine
business
Subjects
Details
- ISSN :
- 17341922
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Archives of Medical Science
- Accession number :
- edsair.doi...........096a41d53a1cfe80892d3de5579ecb33