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A sensitive biosensor of CdS sensitized BiVO4/GaON composite for the photoelectrochemical immunoassay of procalcitonin
- Source :
- Sensors and Actuators B: Chemical. 329:129244
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- In this paper, GaON with excellent photoelectrochemical (PEC) performance was adopted in PEC immunosensor for the first time. Based on CdS sensitized BiVO4/GaON composite material, a label-free PEC immunosensor was successfully developed for determination of procalcitonin (PCT). Firstly, BiVO4 nanoarray was prepared by electrodeposition. Then GaON was added to form the BiVO4/GaON composite material, due to the greatly increasing charge transfer efficiency, the PEC signal increased by about 3 times. At last, CdS grew in situ on BiVO4/GaON composite that further expanded the light absorption range and improved the light utilization, and the PEC signal further increased again. This PEC immunosensor has a good linear relationship of 0.1 pg mL−1 - 50 ng mL−1 and the detection limitation of 0.03 pg mL−1 is calculated. Importantly, the BiVO4/GaON/CdS immunosensor platform showed good specificity and stability, and serum sample analysis have been performed with satisfactory results.
- Subjects :
- Materials science
medicine.diagnostic_test
Composite number
Metals and Alloys
02 engineering and technology
010402 general chemistry
021001 nanoscience & nanotechnology
Condensed Matter Physics
01 natural sciences
0104 chemical sciences
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Linear relationship
Immunoassay
Materials Chemistry
medicine
Electrical and Electronic Engineering
0210 nano-technology
Instrumentation
Biosensor
Charge transfer efficiency
Nuclear chemistry
Subjects
Details
- ISSN :
- 09254005
- Volume :
- 329
- Database :
- OpenAIRE
- Journal :
- Sensors and Actuators B: Chemical
- Accession number :
- edsair.doi...........09b5f61f81653339191a219c4b20306b