Immobilized Enzyme Pipette — ‘Impette’

A new device that uses immobilized enzymes and is called an Immobilized Enzyme Pipette or ‘Impette’ is made by attaching disposable pipette tips made of polymeric nylon tubes containing enzymes attached covalently to their inner surface to the stem of an automatic, adjustable-volume pipette holder. This paper describes the preparation and application of this new device in research laboratories and as a routine analytical device in clinics. Other possible applications are also discussed.