Regulation of Protein Turnover and the Role of Lysosomes

Protein turnover has become an area of increasing interest, both in its own right as a fundamental process in cell biology which is as yet poorly understood, and as a major locus of metabolic regulation. A measure of the interest in this problem is the appearance of several reviews of the field in the last few years (Schimke, 1970; Schimke, 1973).