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Upconversion nanoparticles-MoS2 nanoassembly as a fluorescent turn-on probe for bioimaging of reactive oxygen species in living cells and zebrafish
- Source :
- Sensors and Actuators B: Chemical. 274:180-187
- Publication Year :
- 2018
- Publisher :
- Elsevier BV, 2018.
-
Abstract
- Nanoassemblies for bioimaging in living cells have attracted much attention. In this work, an efficient and sensitive turn-on fluorescent detection platform for reactive oxygen species (ROS) in living cells has been constructed using the nanoassemblies of upconversion nanoparticles (UCNPs)-MoS2 nanoflakes. In this nanostructure, the positively charged UCNPs could assemble with negatively charged poly(acrylic acid) modified MoS2 nanoflakes by electrostatic force, which led to the remarkable fluorescence quenching of UCNPs owing to the excellent quenching ability of MoS2 nanoflakes. In contrast, in the presence of ROS, the fluorescence recovery of UCNPs is successfully realized owing to the decomposition of MoS2 nanoflakes through the chemical reaction with ROS. The ROS-mediated disassembly of the nanoarchitecture display excellent fluorescent response toward ROS. Furthermore, the disassembly of UCNPs-MoS2 nanoflakes has been successfully used for ROS bioimaging in cells and zebrafish.
- Subjects :
- Nanostructure
Nanotechnology
02 engineering and technology
010402 general chemistry
01 natural sciences
Turn (biochemistry)
Upconversion nanoparticles
chemistry.chemical_compound
Materials Chemistry
Electrical and Electronic Engineering
Instrumentation
Zebrafish
Acrylic acid
chemistry.chemical_classification
Reactive oxygen species
Quenching (fluorescence)
biology
Metals and Alloys
021001 nanoscience & nanotechnology
Condensed Matter Physics
biology.organism_classification
Fluorescence
0104 chemical sciences
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
chemistry
0210 nano-technology
Subjects
Details
- ISSN :
- 09254005
- Volume :
- 274
- Database :
- OpenAIRE
- Journal :
- Sensors and Actuators B: Chemical
- Accession number :
- edsair.doi...........0b90624a717bd3932ce93224452479b6