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Sarcopenia Does Not Worsen Survival in Patients With Cirrhosis Undergoing Transjugular Intrahepatic Portosystemic Shunt for Refractory Ascites
- Source :
- American Journal of Gastroenterology. 115:1911-1914
- Publication Year :
- 2020
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2020.
-
Abstract
- Introduction The impact of sarcopenia in patients undergoing transjugular intrahepatic portosystemic shunt (TIPSS) insertion for refractory ascites is unknown. Methods All adult patients who underwent TIPSS insertion for refractory ascites between 2010 and 2018 were included. Skeletal muscle index at L3 was used to determine sarcopenia status. Results One hundred seven patients were followed for 14.2 months. Sarcopenia was present in 57% of patients. No patient had history of pre-TIPSS hepatic encephalopathy (HE). De novo HE occurred in 30% of patients. On multivariate analysis, only platelet count and L3-SMI predicted de novo HE. On multivariate analysis, age and model for end-stage liver disease with sodium predicted mortality, whereas L3-SMI and sarcopenia did not. In patients with repeat imaging, L3-SMI improved significantly post-TIPSS compared with baseline. Discussion Sarcopenia should not be considered as a contraindication to TIPSS insertion in refractory ascites because it is not associated with de novo HE or increased mortality.
- Subjects :
- medicine.medical_specialty
Cirrhosis
Hepatology
medicine.diagnostic_test
business.industry
medicine.medical_treatment
Gastroenterology
medicine.disease
03 medical and health sciences
Liver disease
0302 clinical medicine
030220 oncology & carcinogenesis
Sarcopenia
Internal medicine
Paracentesis
medicine
030211 gastroenterology & hepatology
business
Survival rate
Hepatic encephalopathy
Contraindication
Transjugular intrahepatic portosystemic shunt
Subjects
Details
- ISSN :
- 15720241 and 00029270
- Volume :
- 115
- Database :
- OpenAIRE
- Journal :
- American Journal of Gastroenterology
- Accession number :
- edsair.doi...........0c390edd6b9aad8decd89965bd097fb3