Some peculiarities of metastasis formation by experimental tumors

Metastasis of transplantable malignant tumors is a complicated process in which the localization of the primary tumor and its biological peculiarities together with other factors play an important role. Guerin rat's carcinoma, which metastasizes into internal organs both in subcutaneous inoculation and in its graft into the testicle or into the abdominal cavity, was found to be the most suitable for the study of the laws of metastasis of malignant tumors. Rat's M-1 sarcoma and Y oshida's sarcoma arethe least suitable for the study of this process.