The Impact of Biotechnology on Autoimmunity

Preface. I: Molecular Mechanisms of Autoimmunity. 1. Role of HLA-DQ2 and DQ8 as Susceptibility Molecules in Coeliac Disease -- a Model-Disease of Autoimmunity E. Thorsby, K.E.A. Lundin, L.M. Sollid. 2. Immunoglobulin V Gene Repertoire of Human B Cells R.S. Schwartz. 3. Recent Progress in Human Natural Killer Cell Ontogeny M.C. Mingari, A. Poggi, S. Sivori, N. Pella, C. Vitale, R. Biassoni, L. Moretta. II: Diagnostic Markers in Autoimmune Disease. 4. Role of the HLA-DQ Genotype in IDDM Susceptibility R.S. Accolla, G. Tosi. 5. New Clinical and Molecular Features of 'Essential' Mixed Cryoglobulinemia D. Sansonno, V. Cornacchiulo, A.R. Iacobelli, F. Dammacco. III: Infection and Autoimmunity. 6. Post-Streptococcal Autoimmune Sequelae: a Link between Infection and Autoimmunity M. Kotb. 7. Infection and Autoimmunity: Possible Contribution of Heat Shock Proteins S.H.E. Kaufmann. 8. Chronic Infection and Autoimmunity D.A. Isenberg. 9. The Role of HLS Mimicry by HIV in the Pathogenesis of AIDS A. Dalgleish, L. Brown, B. Souberbielle, M. Westby. 10. Idiotypic Induction of Autoimmune Diseases: a New Aspect of Infection and Autoimmunity Y. Shoenfeld. IV: Clinical Aspects of Autoimmune Diseases. 11. Immunopathology of Insulin-Dependent Diabetes Mellitus (IDDM) J.-F. Bach. 12. Autoimmune Mechanisms in Rheumatoid Synovial Inflammation I. Randen, K.M. Thompson, O. Forre, J.B. Natvig. 13. Antinuclear Antibodies: Clinical and Diagnostic Relevance L. Caponi, R. Neri, A. Tavoni, F. Scamardella, B. Marchini,P. Migliorini, S. Bomdardieri. 14. TAP1 Allele Association with IDDM D.G. Jackson, J.D. Capra. V: Therapeutic Advances in Autoimmune Diseases. 15. Induction of Peripheral Tolerance in Primed Mice L. Adorini, J.-C. Guery. 16. Epitope Screening Libraries: a New Strategy to Identify MHC-Specific Antagonists F. Sinigaglia, J. Hammer. 17. The Therapeutic Use of Anti-CD3 Monoclonal Antibodies in Autoimmune Diseases-Application to Type I Insulin-Dependent Diabetes L. Chatenoud, E. Thervet, J.-F. Bach. 18. Engineering of IL-1 Antagonists D. Boraschi, A. Tagliabue. Index.