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Purity control of the radiopharmaceutical thiamine pyrophosphate-Sn-99mTc

Authors :
P. Busse Grawitz
M. C. Palcos
Source :
Journal of Radioanalytical and Nuclear Chemistry Articles. 88:399-402
Publication Year :
1985
Publisher :
Springer Science and Business Media LLC, 1985.

Abstract

A new purity control method was developed in order to assure the radiochemical purity of thiamine pyrophosphate-Sn-99mTc. The method described consists in ascending cromatography using Whatman No 1 for support and 5% sodium citrate as solvent. It is capable of detecting free99mTcO4− and colloid formation, the most frequent impurities found in99mTc radiopharmaceuticals.

Details

ISSN :
15882780 and 02365731
Volume :
88
Database :
OpenAIRE
Journal :
Journal of Radioanalytical and Nuclear Chemistry Articles
Accession number :
edsair.doi...........0e36e9fd19f6a8acf83938ac9d42e73f