Evaluation of Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios as Reliable Biomarkers for the Diagnosis of Perforated Acute Appendicitis: A Retrospective case control study

Background To investigate the relationship among neutrophil to lymphocyte ratio (NLR),platelet to lymphocyte ratio (PLR) of patients with perforated acute appendicitis and its clinical significance༎ Methods The present study selected 243 patients who underwent appendectomy presented with acute appendicitis from January 2013 and December 2015༎All patients were confirmed by pathology༎AA patients were divided into Perforated acute appendicitis(PAA)group and Non-perforated acute appendicitis༈NPAA༉ group༎The routine blood test results were collected pre-operation and calculated the NLR and PLR༎To analyze the relationship among the NLR,PLR, Age, Gender, WBC count, Operation approach in PAA group and NPAA group. Results The NLR and PLR of PAA group were significantly higher than that of the NPAA group (P