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HPLC and UPLC for Determining Drugs in Blood (A Review)

Authors :
T. A. Yarushok
I. E. Shokhin
Galina V. Ramenskaya
Yu. V. Medvedev
Source :
Pharmaceutical Chemistry Journal. 47:225-230
Publication Year :
2013
Publisher :
Springer Science and Business Media LLC, 2013.

Abstract

The application of HPLC and UPLC techniques to the analysis of drugs in blood plasma during bioequivalence investigations and clinical monitoring was reviewed. Various methods of sample preparation, chromatography, and detection were considered and their specific features were pointed out.

Subjects

Subjects :
Pharmacology
Chromatography
Chemistry
Drug Discovery
Blood plasma
Pharmacology toxicology
Sample preparation
Bioequivalence
High-performance liquid chromatography

Details

ISSN :
15739031 and 0091150X
Volume :
47
Database :
OpenAIRE
Journal :
Pharmaceutical Chemistry Journal
Accession number :
edsair.doi...........0f43c5eb7e4d30fbe8c45d5dc672ea89
Full Text :
https://doi.org/10.1007/s11094-013-0933-2
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