ChemInform Abstract: Synthesis and Antimicrobial Activity of Pyridines Bearing Thiazoline and Thiazolidinone Moieties

Two series of new pyridines bearing thiazoline (3a-n) and thiazolidinone (5a-e) moieties were prepared via the cyclization of the corresponding substituted pyridyl thiourea (2a-g) with an appropriately substituted phenacyl bromide or chloroacetic acid, respectively. The antimicrobial activity was determined for representative compounds and most of them showed moderate activity against Gram-positive bactera.