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STUDY OF THE ANTIDEPRESSANT ACTIVITY OF THE ETHANOLIC EXTRACT OF THE LEAVES OF MORINGA OLEIFERA L. (EEMO) ON ALBINO MICE

Authors :
SHIPRA KAUSHIK
SHOBHIT KAUSHIK
JAYANT RAI
Source :
Asian Journal of Pharmaceutical and Clinical Research. :95-98
Publication Year :
2023
Publisher :
Innovare Academic Sciences Pvt Ltd, 2023.

Abstract

Objectives: The aim of the study is to evaluate the antidepressant activity of the ethanolic extract of the leaves of Moringa oleifera L. (EEMO) on albino mice. Methods: The anti-depressant activity was evaluated using forced swimming test (FST) and tail suspension test (TST). Healthy albino mice were individually forced to swim inside a vertical glass cylinder. Climbing, swimming, and immobility were tested and recorded. In TST, mice were suspended on a string held by a metal stand, and immobility time was recorded. Results: In both FST and TST, it was seen that immobility time decreased with increase in the dose of EEMO. Conclusion: Ethanolic extract of M. oleifera possess anti-depressant activity in a dose dependent manner.

Details

ISSN :
24553891 and 09742441
Database :
OpenAIRE
Journal :
Asian Journal of Pharmaceutical and Clinical Research
Accession number :
edsair.doi...........1038f3dc06568710bcb0aa4adf06bdb5