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Evaluation of Antidepressant Activity of Ethanolic Extract of Abies webbiana and Berberis aristata in Laboratory Animals

Authors :
Alankar Shrivastav
Neetu Sachan
Sucheta Gautam
Dilipkumar Pal
Source :
Journal of Drug Delivery and Therapeutics. 9:244-247
Publication Year :
2019
Publisher :
Society of Pharmaceutical Tecnocrats, 2019.

Abstract

Objective: Abies webbiana and Berberis aristata is an herbal plant that has several therapeutic effects. It also heals depression, grief, nervous stress and tension. In the present study we evaluated anti-depressant effect of ethanolic extract from Abies webbiana and Berberis aristata by using Forced Swimming Test (FST) and Tail Suspension Test (TST). Methods: Two doses of ethanolic extract of Abies webbiana and berberis aristata (200 mg/kg and 400 mg/kg) was given orally. Immobility time were measured after 30 min after the dosing and compared with control group and Flouxetine (25mg/kg) as a standard group. Results: The ethanolic extract of BA and AW (400 mg/kg) was found to be effective and it exhibited activity similar to that of the conventional drug Flouxetine (25mg/kg) (p

Details

ISSN :
22501177
Volume :
9
Database :
OpenAIRE
Journal :
Journal of Drug Delivery and Therapeutics
Accession number :
edsair.doi...........10c3f1be1b88887c66e04885a566aef4
Full Text :
https://doi.org/10.22270/jddt.v9i1.2290