ChemInform Abstract: Methylene Piperazine-2,5-diones as Templates for the Synthesis of Amino Acid Derivatives

Methylene piperazine-2,5-diones 5a and 5b are important synthetic intermediates. The preparation as well as the use of these compounds in the synthesis of amino acid derivatives are described. Our studies demonstrate that excellent chiral induction in carbon-carbon bond forming reactions can be obtained with methylene piperazinedione 5b .