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Correlating immune toxicity, blood cell counts, and overall survival in cancer patients receiving immune therapy

Authors :
Shaheen Khan
Benjamin Aaron Bleiberg
Donglu Xie
Murtaza Ahmed
Mary Katherine Watters
Jason Y. Park
Jessica Saltarski
Saad A. Khan
Farjana J. Fattah
Edward K. Wakeland
Vinita Popat
David Hsieh
Rong Lu
David E. Gerber
Yvonne Gloria-McCutchen
Mitchell S. von Itzstein
Source :
Journal of Clinical Oncology. 38:3043-3043
Publication Year :
2020
Publisher :
American Society of Clinical Oncology (ASCO), 2020.

Abstract

3043 Background: Baseline circulating white blood cell differential counts have been proposed as possible markers of response to Immune therapy (ICI) and immune toxicity (irAE), but have not been validated for clinical practice. Methods: 214 patients with various cancers receiving ICI had clinical lab results and overall/organ specific irAE analyzed. Absolute lymphocyte (ALC), eosinophil (AEC) and neutrophil (ANC) counts

Details

ISSN :
15277755 and 0732183X
Volume :
38
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........118552adf45d06d67efdefa4e4e0af28
Full Text :
https://doi.org/10.1200/jco.2020.38.15_suppl.3043