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Prevalence of acute kidney injury network (AKIN) in pediatric non acetaminophen acute liver failure (pNA-ALF) & addition of akin staging to king's college criteria (Kcc) in pNA-ALF improves prognostic value

Authors :
Veena Raghunathan
Maninder Dhaliwal
Sakshi Karkra
Neelam Mohan
Source :
Journal of Clinical and Experimental Hepatology. 3:S17
Publication Year :
2013
Publisher :
Elsevier BV, 2013.

Abstract

A cu te Li ve r Fa ilu re from malnutrition, a host factor known to cause reduced immunocompetence leading to greater risk of multiple viral infections. Aims: To evaluate the role of maternal nutritional factors in acute viral hepatitis (AVH) and acute liver failure (ALF) patients with HEV infection during pregnancy. Methods: The study included 180 pregnant cases of which 72 HEV infected pregnant cases, 78 Non-HEV pregnant cases and 30 control cases were recruited in the study during February 2011 to December 2012. Serological evaluation of virological markers like IgM anti-HAV, HBsAg, anti-HCV Ab and IgM anti-HEV was done by ELISA. Nutritional factors were evaluated by measuring the anthropometric parameters such as body mass index (BMI), height, weight, triceps skin fold thickness, mid arm circumference (MAC), arm span using appropriate readings. Results: The meanmaternal age, gestational age at delivery and hemoglobin levels of HEV infected pregnant patients were 24.32+4.25years, 33.41+3.94weeks and 10.4+1.87 g/ dl respectively. BMI, mid arm circumference and tricep skin fold thickness were found to be significantly lower in ALF pregnant patients compared to their AVH counterparts in the HEV group (P

Details

ISSN :
09736883
Volume :
3
Database :
OpenAIRE
Journal :
Journal of Clinical and Experimental Hepatology
Accession number :
edsair.doi...........1217bad2eee9451f38e40392a282c36b
Full Text :
https://doi.org/10.1016/j.jceh.2013.03.037