P3‐320: Pharmacokinetic and pharmacodynamic investigation of ELND006, a novel APP‐selective gamma‐secretase inhibitor, on amyloid‐β concentrations in the brain, CSF and plasma of multiple nonclinical species following oral administration

Subjects

Subjects :

Amyloid β
Epidemiology
business.industry
Health Policy
Pharmacology
Psychiatry and Mental health
Cellular and Molecular Neuroscience
Developmental Neuroscience
Pharmacokinetics
Oral administration
Pharmacodynamics
Medicine
Neurology (clinical)
Geriatrics and Gerontology
business
Gamma secretase

Details

ISSN :

15525279 and 15525260

Volume :

6

Database :

OpenAIRE

Journal :

Alzheimer's & Dementia

Accession number :

edsair.doi...........127d5c0d44fb9c1d3c3a28cac08a1ae5

Full Text :

https://doi.org/10.1016/j.jalz.2010.05.1821