Sklerodermie im Kindes- und Jugendalter

From a clinical point of view scleroderma is classified as either localized scleroderma or systemic scleroderma. However, as this didactic separation does not always reflect the clinical picture in patients, various groups have attempted to make new classification methods. This current review focuses on the clinical presentation in this respect, recently developed aspects of etiology and molecular pathogenesis in addition to modern aspects of therapeutic strategies.