A synthesis of a γ-azetidinyl-β-hydroxy-α-amino acid derivative, a key intermediate for the synthesis of mugineic acid

The γ-azetidinyl-β-hydroxy-α-amino acid derivative 2, a key intermediate for the total synthesis of mugineic acid (1), was stereoselectively prepared from readily available (2R,3R)-epoxysuccinic acid (3).