Does Disseminated Nontuberculous Mycobacterial Disease Cause False-Positive Determine TB-LAM Lateral Flow Assay Results? A Retrospective Review

Authors :: Jeremy Nel
Christopher K Lippincott
David C. Spencer
Prudence Ive
Ian Sanne
Rebecca Berhanu
Source :: Clinical Infectious Diseases. 65:1226-1228
Publication Year :: 2017
Publisher :: Oxford University Press (OUP), 2017.
Abstract: We retrospectively reviewed the Determine TB-LAM lateral flow assay (LF-LAM) results among human immunodeficiency virus-infected patients with disseminated nontuberculous mycobacterial (NTM) disease. LF-LAM was positive in 19 of 21 patients without evidence of tuberculosis (TB) coinfection. Although TB-NTM coinfection may have been underdiagnosed, our results suggest that disseminated NTM disease may cause false-positive LF-LAM results.

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