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A phase 3, randomized, double-blind study of luspatercept (ACE-536) in patients (pts) with Revised International Prognostic Scoring System (IPSS-R) very low- to intermediate-risk myelodysplastic syndromes (MDS) with ring sideroblasts (RS) who require red blood cell (RBC) transfusions: The MEDALIST trial
- Source :
- Journal of Clinical Oncology. 34:TPS7076-TPS7076
- Publication Year :
- 2016
- Publisher :
- American Society of Clinical Oncology (ASCO), 2016.
-
Abstract
- TPS7076Background: Management of anemia is a common therapeutic challenge in pts with MDS. Approx. 30% of MDS pts have ≥ 15% RS in the bone marrow (BM) accompanied by ineffective erythropoiesis. Lu...
- Subjects :
- Ineffective erythropoiesis
Cancer Research
medicine.medical_specialty
Pediatrics
business.industry
Anemia
Myelodysplastic syndromes
macromolecular substances
Ring sideroblasts
medicine.disease_cause
medicine.disease
Gastroenterology
carbohydrates (lipids)
stomatognathic diseases
Red blood cell
medicine.anatomical_structure
Oncology
International Prognostic Scoring System
hemic and lymphatic diseases
Internal medicine
Luspatercept
otorhinolaryngologic diseases
Medicine
Bone marrow
business
Subjects
Details
- ISSN :
- 15277755 and 0732183X
- Volume :
- 34
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Oncology
- Accession number :
- edsair.doi...........17aa90b9feef493505adcfab76171b47
- Full Text :
- https://doi.org/10.1200/jco.2016.34.15_suppl.tps7076