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A phase 3, randomized, double-blind study of luspatercept (ACE-536) in patients (pts) with Revised International Prognostic Scoring System (IPSS-R) very low- to intermediate-risk myelodysplastic syndromes (MDS) with ring sideroblasts (RS) who require red blood cell (RBC) transfusions: The MEDALIST trial

Authors :
Aziz Benzohra
Bond Vo
Guillermo Garcia-Manero
Ghulam J. Mufti
Kenneth M. Attie
Mikkael A. Sekeres
Uwe Platzbecker
Rami S. Komrokji
Abderrahmane Laadem
Pierre Fenaux
Alan F. List
Jennie Zhang
Source :
Journal of Clinical Oncology. 34:TPS7076-TPS7076
Publication Year :
2016
Publisher :
American Society of Clinical Oncology (ASCO), 2016.

Abstract

TPS7076Background: Management of anemia is a common therapeutic challenge in pts with MDS. Approx. 30% of MDS pts have ≥ 15% RS in the bone marrow (BM) accompanied by ineffective erythropoiesis. Lu...

Details

ISSN :
15277755 and 0732183X
Volume :
34
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........17aa90b9feef493505adcfab76171b47
Full Text :
https://doi.org/10.1200/jco.2016.34.15_suppl.tps7076