Finite element modeling of dielectrophoretic microelectrodes based on a array and ratchet type

This research describes an investigation of nonuniform electric field for dielectrophoretic forces (F DEP ) application in particles and cells manipulation. In an electro kinetics occurrence, a miniaturized array and ratchet type microelectrodes has been simulated. The study of optimal F DEP behavior on the electric field distribution for both type microelectrodes was characterized and optimized by finite element method, (FEM). A set of array and ratchet type microelectrode are biased to generate asymmetric electric field distribution. Normalization of microelectrode simulation result shows that array and ratchet type produced a comparable electric field strength and direction. Deployment of additional dimension for array type electrode, three poles produced the highest of electric field strength of 7.513 e7 V/m and displacement field direction of 2.758 e−3 C/m2. Simulation results are used to design a higher sensitive and selective of a dielectrophoretic (DEP) microelectrode for selection, collection and processing of particle and cell using optimal F DEP that determination advancement in the development of dielectrophoretic a lab-on-a-chip. Ultimately, the findings of this work is possible to contribute in medical sciences research for the enrichment of stem cell from bone narrow and peripheral blood form via integration DEP into a lab on a chip, (DLOC) concept application.