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Asymmetric Synthesis of β-Lactam via Palladium-Catalyzed Enantioselective Intramolecular C(sp3)–H Amidation

Authors :
Gong Chen
Xiaoyan Lv
Huarong Tong
Peng Liu
Wenrui Zheng
Gang He
Source :
ACS Catalysis. 10:114-120
Publication Year :
2019
Publisher :
American Chemical Society (ACS), 2019.

Abstract

β-Lactams are important scaffolds in drug design and frequently used as reactive intermediates in organic synthesis. Catalytic reactions featuring intramolecular C–H amidation of alkyl carboxamide ...

Details

ISSN :
21555435
Volume :
10
Database :
OpenAIRE
Journal :
ACS Catalysis
Accession number :
edsair.doi...........1920076754b8894aa982f4ee4ffa1678
Full Text :
https://doi.org/10.1021/acscatal.9b04768