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Identification and genotoxicity evaluation of potential impurities in rabeprazole sodium using in silico and in vitro analyses

Authors :
Yi Du
Yihong Lu
Li Tan
Yang Liu
Tiantian Cai
Yinnan Wu
Changhong Meng
Yuxin Wang
Source :
Drug and Chemical Toxicology. 45:2116-2122
Publication Year :
2021
Publisher :
Informa UK Limited, 2021.

Abstract

Rabeprazole sodium is a widely used drug for gastrointestinal disorders. Several analytical methods for identifying rabeprazole sodium and its impurities have been reported. However, the genotoxici...

Details

ISSN :
15256014 and 01480545
Volume :
45
Database :
OpenAIRE
Journal :
Drug and Chemical Toxicology
Accession number :
edsair.doi...........1a07f9a924a3d77aebd49d582f9a0649