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Stereoelectronic effects on metallation of 1,3-dioxanes

Authors :
Albert I. Meyers
Anthony G. Abatjoglou
Campbell Arthur L
Ernest L. Eliel
Source :
Tetrahedron Letters. 20:4159-4162
Publication Year :
1979
Publisher :
Elsevier BV, 1979.

Abstract

Metallation of the acetal (H-2) proton in 1,3-dioxolanes, 1,3-dioxanes and open chain acetals is possible only if the proton can occupy an “equatorial-like” conformation.

Details

ISSN :
00404039
Volume :
20
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........1c1c1310503ebb28d57a9b031c29908b
Full Text :
https://doi.org/10.1016/s0040-4039(01)86532-1