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Metabolic characteristics of obese children with fatty liver

Authors :
Kanglu Zhao
Hongzhen Ju
Haili Wang
Source :
Medicine. 98:e14939
Publication Year :
2019
Publisher :
Ovid Technologies (Wolters Kluwer Health), 2019.

Abstract

To investigate metabolic differences between simple obese children and those comorbid with fatty liver disease.Obese children hospitalized in our center from 2014 to 2016 were included and divided into simple obese group and obese with fatty liver group by ultrasound-based diagnosis of fatty liver. Epidemiology data and serum biochemical studies were recorded. Body Mass Index (BMI) and homeostasis model insulin resistance index (HOMA-IR) were calculated accordingly.A total of 186 obese children were enrolled in this study, including 93 cases of obese children and 93 obese patients' comorbid with fatty liver. The proportion of male, age, waist circumference (WC), BMI, fasting blood-glucose (FBG), glycosylated hemoglobin A1c (HbA1c), fasting insulin (FINS), and HOMA-IR were significantly higher in obese patients with fatty liver (P 1, P

Details

ISSN :
15365964 and 00257974
Volume :
98
Database :
OpenAIRE
Journal :
Medicine
Accession number :
edsair.doi...........1c2d8141816cc481bef5255253a3355e
Full Text :
https://doi.org/10.1097/md.0000000000014939