Pharmacokinetics of Hu5F9-G4, a first-in-class anti-CD47 antibody, in patients with solid tumors and lymphomas

Authors :: Bing Wang
Rochelle Secreto
Balaji Agoram
Mark P. Chao
Nehal Lakhani
Branimir I. Sikic
Chris H. Takimoto
Amita Patnaik
Jie Liu
Source :: Journal of Clinical Oncology. 36:2525-2525
Publication Year :: 2018
Publisher :: American Society of Clinical Oncology (ASCO), 2018.
Abstract: 2525Background: Hu5F9-G4 is a humanized monoclonal antibody targeting CD47, a “don’t eat me” signal on cancer cells, that stimulates tumor cell phagocytosis and activates an anti-tumor T-cell respo...

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