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Comparative assessment of metabolic, hormonal and psychological characteristics of young obese men
- Source :
- Clinical Medicine (Russian Journal). 95:829-835
- Publication Year :
- 2017
- Publisher :
- Medical Informational Agency Publishers, 2017.
-
Abstract
- Aim. To study metabolic-hormonal status and psychological characteristics of young obese men. Material and methods. The study included 87 young obese men (BMI ≥30 kg/m2) aged 16-25 yr given medication or non-medication treatment for 12 weeks. Blood glucagon-like peptide-1 (GLP-1), insulin, and glucose levels were measured after orlistat intake. Final screening included biochemical and hormonal studies. 48 patients underwent psychological testing. Results. Orlistat therapy resulted in clinically significant reduction of body mass (by more than 5% in 50% of the patients). Cortisol level also decreased while testosterone level increased. Meal test revealed elevated baseline GLP-1 level in 77,7% of the patients. There was correlation between baseline GLP-1 and insulin levels (r=0,61; р=0,001). Orlistat therapy decreased anxiety and depression (p
- Subjects :
- business.industry
Physiology
Medicine
General Medicine
business
Hormone
Subjects
Details
- ISSN :
- 24121339 and 00232149
- Volume :
- 95
- Database :
- OpenAIRE
- Journal :
- Clinical Medicine (Russian Journal)
- Accession number :
- edsair.doi...........1db916f8e45ed009ba8cfb672e07d9d2