Safety, Pharmacokinetics and Pharmacodynamics of TD-0714, a Novel Non-Renally Cleared Neprilysin Inhibitor, in Healthy Humanvolunteers: Potential for Once-Daily Dosing and Predictable Exposure in Patients Regardless of Baseline Renal Function

Authors :: Kenneth Colley
Jitendra Kanodia
Kefei Zhou
Denise Wang
Arthur Lo
David L. Bourdet
Jonathan Lee
Whedy Wang
Michael Baldwin
Source :: Journal of Cardiac Failure. 23:S68
Publication Year :: 2017
Publisher :: Elsevier BV, 2017.

Subjects :: Pharmacokinetics
business.industry
Anesthesia
Renal function
Medicine
In patient
Pharmacology
Cardiology and Cardiovascular Medicine
Once daily dosing
business
Neprilysin
Clearance

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